| 产品详情 |
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| Antigenic Specificity | CD45RC |
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| Clone | OX-22 |
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| Host Species | Mouse |
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| Reactive Species | rat |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | 250 ug |
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| Concentration | n/a |
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| Applications | Flow Cytometry: 0.1 µg/1x10^6 cells, Immunohistochemistry (Frozen): Assay Dependent |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CD45RC Monoclonal Antibody (OX-22). CD45RC (PTPRC) is a protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. It acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, the second affects the substrate specificity of the first. Upon T-cell activation, CD45RC recruits and dephosphorylates SKAP1 and FYN. Mutations of the gene can result in severe combined immunodeficiency and multiple sclerosis. |
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| Immunogen | n/a |
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| Other Names | B220, CD45R, Cd45, Ly-5, Lyt-4, T200, cluster designation 45RC |
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| Gene, Accession # | Entrez: 24699; Uniprot: P04157 |
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| Catalog # | MA1-70013 |
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| Price | |
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| Order / More Info | CD45RC Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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