产品详情 |
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Antigenic Specificity | GRASP1 |
Clone | OTI1E3 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | purified |
Size | 100 µl |
Concentration | n/a |
Applications | Flow Cytometry: 1:100, Immunocytochemistry: 1:100, Immunofluorescence: 1:100, Immunohistochemistry (Paraffin): 1:50, Western Blot: 1:1000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | GRASP1 Monoclonal Antibody (OTI1E3). PDZ domain-containing proteins, such as PSD-95 and GRIP are thought to play key roles in glutamate receptor plasticity. GRIP-associated proteins (GRASPs) that bind to distinct PDZ domains within GRIP also play key roles in regulation of glutamate receptor function. GRASP-1 is a neuronal rasGEF associated with GRIP and AMPA receptors in vivo (Scannevin and Huganir, 2000). Recent work suggests that GRASP-1 may regulate neuronal ras signaling and contribute to the regulation of AMPA receptor distribution by NMDA receptor activity (Ye et al., 2000). |
Immunogen | n/a |
Other Names | GRASP-1, GRIP-1, GRIP1, GRIPAP1, KIAA1167, GRIP1-associated protein 1 |
Gene, Accession # | Entrez: 56850; Uniprot: Q4V328 |
Catalog # | MA5-25035 |
Price | |
Order / More Info | GRASP1 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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