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| Antigenic Specificity | Phospho-TERT (Ser1125) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 400 µL |
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| Concentration | n/a |
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| Applications | Dot blot: 1:500 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Phospho-TERT (Ser1125) Polyclonal Antibody. Telomerase is a ribonucleoprotein polymerase that maintains telomere ends by addition of the telomere repeat TTAGGG. The enzyme consists of a protein component with reverse transcriptase activity, and an RNA component which serves as a template for the telomere repeat. Telomerase expression plays a role in cellular senescence, as it is normally repressed in postnatal somatic cells resulting in progressive shortening of telomeres. Deregulation of telomerase expression in somatic cells may be involved in oncogenesis. Studies in mouse suggest that telomerase also participates in chromosomal repair, since de novo synthesis of telomere repeats may occur at double-stranded breaks. |
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| Immunogen | n/a |
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| Other Names | Telomerase reverse transcriptase; Telomerase catalytic subunit; HEST2; Telomerase-associated protein 2; TP2; EST2; TCS1; TRT; hTERT |
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| Gene, Accession # | Entrez: 7015; Uniprot: O14746 |
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| Catalog # | PA5-12973 |
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| Price | |
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| Order / More Info | Phospho-TERT (Ser1125) Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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