产品详情 |
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Antigenic Specificity | Phospho-TIP60 (Ser86) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | Western Blot: 1:500-1:1000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Phospho-TIP60 (Ser86) Polyclonal Antibody. TIP60 is a transcription factor, originally isolated as an HIV-1 TAT-interactive protein, known to interact with the viral TAT protein that leads to HTATIP polyubiquitination and targets it for degradation. It belongs to the MYST family of histone acetyl transferases (HATs). TIP60 is a catalytic subunit of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. A co-regulator of transcription factors, TIP60 either promotes or suppresses tumorigenesis. TIP60 is an enzyme that has a role in DNA repair and apoptosis and is thought to play an important role in signal transduction. |
Immunogen | n/a |
Other Names | ESA1, HTATIP, HTATIP1, PLIP, TIP, cPLA2 |
Gene, Accession # | Entrez: 10524, 81601; Uniprot: Q8CHK4, Q92993 |
Catalog # | PA5-38424 |
Price | |
Order / More Info | Phospho-TIP60 (Ser86) Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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