产品详情 |
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Antigenic Specificity | Phospho-TLK1 (Ser743) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | purified |
Size | 100 µl |
Concentration | n/a |
Applications | Western Blot: 1:500-1:1000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Phospho-TLK1 (Ser743) Polyclonal Antibody. The Tousled-like kinases (TLK1 and TLK2, also designated PKU-beta and PKU-alpha, respectively) are the human homologs of the Tousled gene from Arabidopsis thaliana, which encodes a Serine/Threonine kinase that is necessary for proper organ morphogenesis. Both TLKs contain a nuclear localization signal and a predicted coiled-coil region in the N-terminal domain. TLK is ubiquitously expressed, and is prevalent in mouse testis, especially in pachytene spermatocytes and round spermatids. It displays a propensity to dimerize through an interaction between its coiled-coil structure and is able to autophosphorylate, as well as phosphorylate exogenous substrates. TLK1 and TLK2 are regulated by the cell cyc |
Immunogen | n/a |
Other Names | Serine/threonine-protein kinase tousled-like 1, PKU-beta, Tousled-like kinase 1, TLK-1, KIAA0137, PKU-beta, PKU beta, PKU beta |
Gene, Accession # | Entrez: 228012, 311118, 9874; Uniprot: Q8C0V0, Q9UKI8 |
Catalog # | PA5-37340 |
Price | |
Order / More Info | Phospho-TLK1 (Ser743) Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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