| 产品详情 |
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| Antigenic Specificity | Phospho-TrkA/TrkB (Tyr490, Tyr516) |
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| Clone | H.652.3 |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | IgG |
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| Format | purified |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | Immunoprecipitation: 1:50, Western Blot: 1:1000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Phospho-TrkA/TrkB (Tyr490, Tyr516) Monoclonal Antibody (H.652.3). This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date. |
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| Immunogen | n/a |
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| Other Names | Oncogene TRK; TRK1-transforming tyrosine kinase protein; high affinity nerve growth factor receptor; tyrosine kinase receptor A |
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| Gene, Accession # | Entrez: 18211, 18212, 25054, 4914, 4915, 59109; Uniprot: P04629, P15209, P35739, Q16620, Q3UFB7, Q63604 |
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| Catalog # | MA5-14926 |
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| Price | |
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| Order / More Info | Phospho-TrkA/TrkB (Tyr490, Tyr516) Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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