| 产品详情 |
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| Antigenic Specificity | Phospho-TrkA (Tyr490) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | Immunoprecipitation: 1:100, Western Blot: 1:1000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Phospho-TrkA (Tyr490) Polyclonal Antibody. TrkA (tropomyosin receptor kinase A) encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. TrkA is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of TrkA leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in TrkA have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date. Mutations in the TRKA gene have been associated with congenital insensitivity to pain, anhidro |
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| Immunogen | n/a |
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| Other Names | Oncogene TRK; TRK1-transforming tyrosine kinase protein; high affinity nerve growth factor receptor; tyrosine kinase receptor A |
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| Gene, Accession # | Entrez: 18211, 4914, 59109; Uniprot: P04629, P35739, Q3UFB7 |
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| Catalog # | PA5-17877 |
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| Price | |
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| Order / More Info | Phospho-TrkA (Tyr490) Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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