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Antigenic Specificity | Phospho-TrkB (Tyr515) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | purified |
Size | 100 µl |
Concentration | n/a |
Applications | Immunohistochemistry (Paraffin): 1:50-1:200, Western Blot: 1:500-1:1000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Phospho-TrkB (Tyr515) Polyclonal Antibody. TrkB is a receptor tyrosine kinase of the Trk family. Receptor for brain-derived neurotrophic factor (BDNF), neurotrophin-3, -4 and -5 but not nerve growth factor (NGF). TrkB is involved in the development and maintenance of the nervous system. Moreover, Trk B is a tyrosine kinase gene highly related to Trk A. Trk B expression is confined to tissues within the central and peripheral nervous systems. The brain-derived neurotrophic factor (BDNF) and NT-3, but not NGF, can induce rapid phosphorylation on tyrosine of Trk B gp145, one of the receptors encoded by Trk B, although BDNF elicits a response at least two orders of magnitude greater than NT-3. TrkB is a membrane-bound receptor that, upon neurot |
Immunogen | n/a |
Other Names | AI848316, BDNF tropomyosine receptor kinase B, BDNF/NT 3 growth factors receptor, BDNF/NT-3 growth factors receptor, Brain derived neurotrophic factor receptor, C030027L06Rik, EC 2.7.10.1, GP145 TrkB, GP145-TrkB, GP145-TrkB/GP95-TrkB, GP95 TrkB, GP95-TrkB, neurotrophic tyrosine kinase receptor type 2, Neurotrophin receptor tyrosine kinase type 2, NTRK 2, NTRK2, NTRK2, Obesity, hyperphagia, and developmental delay, included, RATTRKB1, Tkrb, Trk B, Trk-B, TRKB, TrkB tyrosine kinase, TRKB1, Tropomyosin related kinase |
Gene, Accession # | Entrez: 18212, 25054, 4915; Uniprot: P15209, Q16620, Q63604 |
Catalog # | PA5-36695 |
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Order / More Info | Phospho-TrkB (Tyr515) Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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