产品详情 |
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Antigenic Specificity | Cardiotin |
Clone | SR-3 |
Host Species | Mouse |
Reactive Species | human, porcine |
Isotype | IgM |
Format | purified |
Size | 100 µL |
Concentration | n/a |
Applications | Immunohistochemistry (Frozen): 1:100-1:200, Western Blot: 1:100-1:500 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Cardiotin Monoclonal Antibody (SR-3). Cardiotin is a high molecular weight protein complex (~300 kDa) located in the mitochondria of cardiomyocytes and skeletal muscle. The cardiotin structure exists of subunits of ~60 kDa and ~100 kDa, probably in a tetrameric configuration. Both subunits contain the same amino-terminal 14 amino-acid sequence, showing high homology to human skeletal muscle alpha-actinin. During cardiac contractile dysfunction and myocard cell differentiation, the cardiotin distribution is affected. Compared to other structural proteins, cardiotin is one of the first to respond to insults (ischemia, fibrillation) that influence the functional status of cardiomyocytes. |
Immunogen | n/a |
Other Names | n/a |
Gene, Accession # | n/a |
Catalog # | MA1-06309 |
Price | |
Order / More Info | Cardiotin Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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