产品详情 |
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Antigenic Specificity | Cardiotrophin 1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | purified |
Size | 100 µl |
Concentration | n/a |
Applications | Immunohistochemistry (Paraffin): 1:50-1:200, Western Blot: 1:500-1:1000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Cardiotrophin 1 Polyclonal Antibody. Cardiotrophin-1 (CT-1) is a member of the IL-6 family of cytokines, which signal through gp130 receptor complexes. gp130 complexes with several different receptor subunits to transmit signals from Cardiotrophin-1, IL-6, LIF, OSM, CNTF and IL-11. Cardiotrophin-1 binds to and activates the leukemia inhibitory factor (LIF) receptor/gp130 receptor complex and has been shown to induce hypertrophy in cardiac myocytes in vitro. Cardiotrophin-1, a secreted protein expressed at high levels in myocardium during cardiogenesis, has been shown to promote proliferation and survival of embryonic cardiomyocytes, suggesting a role for Cardiotrophin-1 in the activation of gp130 during cardiac development. |
Immunogen | n/a |
Other Names | Cardiotrophin-1; CT-1; CTF1; Cardiotrophin1; CT1; Cardiotrophin 1; CT 1; |
Gene, Accession # | Entrez: 13019, 1489, 29201; Uniprot: Q16619, Q60753, Q63086 |
Catalog # | PA5-75447 |
Price | |
Order / More Info | Cardiotrophin 1 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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