| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | CARF |
|---|
| Clone | polyclonal |
|---|
| Host Species | Rabbit |
|---|
| Reactive Species | human |
|---|
| Isotype | n/a |
|---|
| Format | purified |
|---|
| Size | 100 µl |
|---|
| Concentration | n/a |
|---|
| Applications | Immunohistochemistry: 1:50-1:200 |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | CARF Polyclonal Antibody. CARF (calcium-response factor), also known as ALS2CR8 (amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 protein) or NYD-SP24, is a 725 amino acid nuclear protein. Expressed in a wide variety of tissues with highest expression in the hippocampus, CARF is thought to be a transcription factor that associates with the p53 tumor suppression pathway. CARF cooperates, co-localizes and is co-regulated with ARF, an ADP-ribosylation factor, and, through this interaction, helps to mediate ARF-p53-induced apoptotic signaling. This apoptotic pathway is implicated in cell cycle control, proper cellular development, response to DNA damage and the aging process, suggesting that CARF participates in various event |
|---|
| Immunogen | n/a |
|---|
| Other Names | Als2cr8 |
|---|
| Gene, Accession # | Entrez: 79800; Uniprot: Q8N187 |
|---|
| Catalog # | PA5-56973 |
|---|
| Price | |
|---|
| Order / More Info | CARF Antibody from INVITROGEN ANTIBODIES |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|