产品详情 |
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Antigenic Specificity | MCL1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 1 mL |
Concentration | n/a |
Applications | Immunohistochemistry (Paraffin): 1:100 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | MCL1 Polyclonal Antibody. MCL-1 (Myeloid cell leukemia-1) is a member of the BCL-2 family. The carboxy terminal of MCL-1 and BCL-2 share significant sequence homology. Expression of MCL-1 is increased upon exposure of ML-1 cells to various types of DNA damaging agents (e.g. ionizing radiation, ultraviolet radiation, and alkylating drugs) along with increases in GADD45 and Bax and a decrease in BCL-2. Like BCL-2, MCL-1 has the capacity to promote cell viability under conditions that otherwise cause apoptosis. |
Immunogen | n/a |
Other Names | BCL2L3, EAT, MCL1-ES, MCL1L, MCL1S, Mcl-1, TM, bcl2-L-3, mcl1/EAT, bcl-2-like protein 3, bcl-2-related protein EAT/mcl1, induced myeloid leukemia cell differentiation protein Mcl-1, myeloid cell leukemia ES |
Gene, Accession # | Entrez: 4170; Uniprot: Q07820 |
Catalog # | PA1-38096 |
Price | |
Order / More Info | MCL1 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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