产品名称 MCL-1 Antibody from INVITROGEN ANTIBODIES
产品货号 14-6701-82
产品价格 现货询价,电话:010-67529703
产品规格 100 µg
产品品牌 INVITROGEN ANTIBODIES
产品概述
产品详情
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Antigenic SpecificityMCL-1
CloneAb22
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1, kappa
Formatpurified
Size100 µg
Concentrationn/a
ApplicationsImmunocytochemistry: 5 µg/mL, Immunofluorescence: 5 µg/mL, Western Blot: 5 µg/mL
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DescriptionMCL-1 Monoclonal Antibody (Ab22), eBioscience™. Mcl-1 (Myeloid cell leukemia-1) is a member of the bcl-2 family. The carboxy terminal of Mcl-1 and bcl-2 share significant sequence homology. Expression of Mcl-1 is increased upon exposure of ML-1 cells to various types of DNA damaging agents (e.g. ionizing radiation, ultraviolet radiation, and alkylating drugs) along with increases in GADD45 and Bax and a decrease in bcl-2. Enhanced expression of Mcl-1, prominently associated with mitochondria, complements the continued expression of bcl-2 in ML-1 cells undergoing differentiation. Like bcl-2, Mcl-1 has the capacity to promote cell viability under conditions that otherwise cause apoptosis.
Immunogenn/a
Other Namesbcl-2-like protein 3; bcl-2-related protein EAT/mcl1; EAT; MCL1L; MCL1S; MGC104264; MGC1839; myeloid cell leukemia 1; myeloid cell leukemia ES; myeloid cell leukemia sequence 1 (BCL2-related)
Gene, Accession #Entrez: 4170; Uniprot: Q07820
Catalog #14-6701-82
Price
Order / More InfoMCL-1 Antibody from INVITROGEN ANTIBODIES
Product Specific Referencesn/a
产品资料