产品详情 |
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Antigenic Specificity | DNA Adenine Methylase |
Clone | RAB-50 |
Host Species | Mouse |
Reactive Species | n/a |
Isotype | IgG1 |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | Western Blot: 5-10 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | DNA Adenine Methylase Monoclonal Antibody (RAB-50). DNA adenine methylase (DAM) is an enzyme that methylates adenine residues in the 4-base pair DNA sequence, GATC. This methylation reaction has been shown to be crucial in a variety of cellular processes in bacteria. These include (i) the control of initiation of DNA replication (GATC occurs 11 times in the highly conserved bacterial origin of replication sequence); (ii) methyldirected mismatch repair; (iii) control of transposition of certain transposable DNA elements; and (iv) control of gene expression. With regard to gene expression, the recent report by Heithoff et al. (Science; 284:967-970; 1999) showed that the deletion of the DAM gene rendered Salmonella typhimurium totally avirulen |
Immunogen | n/a |
Other Names | n/a |
Gene, Accession # | n/a |
Catalog # | MA1-12717 |
Price | |
Order / More Info | DNA Adenine Methylase Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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