产品详情 |
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Antigenic Specificity | RRAS |
Clone | 6A8 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2b |
Format | purified |
Size | 100 µL |
Concentration | n/a |
Applications | Western Blot: 1:2000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | RRAS Monoclonal Antibody (6A8). The Ras superfamily of small GTPases includes the Ras, Rho, Arf, Rab, and Ran families. Ras-regulated signal pathways control such as actin cytoskeletal integrity, proliferation, differentiation, cell adhesion, apoptosis, and cell migration. These GTPases function as molecular switches that control eukaryotic cell function by cycling between two interconvertible forms, a GDP-bound inactive form and a GTP-bound active form. The binding of GTP leads to a conformational change in the downstream effector-binding domain of the G-protein. The small GTPases are monomeric G-proteins with molecular masses over the range 20-30 kDa. Ras is attached to the cell membrane by prenylation. Mutations in the Ras family of prot |
Immunogen | n/a |
Other Names | Oncogene RRAS; p23; ras-related protein R-Ras |
Gene, Accession # | Entrez: 6237; Uniprot: P10301 |
Catalog # | MA5-17211 |
Price | |
Order / More Info | RRAS Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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