产品详情 |
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Antigenic Specificity | RRAS2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | purified |
Size | 100 µl |
Concentration | n/a |
Applications | Western Blot: 1:500-1:2000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | RRAS2 Polyclonal Antibody. Activating mutations and overexpression of classical Ras subfamily members (K-RAS, N-RAS and H-RAS) have been widely investigated as key events in the development of human cancers. The RRAS subfamily of Ras-related proteins includes RRAS1, RRAS2 (TC21) and RRAS3 (M-Ras) show overall amino acid identity with the classical Ras subfamily (H-Ras, K-Ras and N-Ras) of 55-60%. RRAS2 is a small GTPbinding protein of the Ras superfamily of GTPases. It might transduce growth inhibitory signals across the cell membrane, exerting its effect through an effector shared with the Ras proteins. RRAS2 has high oncogenic potential and overexpression/mutations have been reported in several tumor tissues and cell lines. |
Immunogen | n/a |
Other Names | Ras-related protein R-Ras2; Ras-like protein TC21; Teratocarcinoma oncogene; TC21 |
Gene, Accession # | Entrez: 22800, 365355, 66922; Uniprot: P62070, P62071 |
Catalog # | PA5-77123 |
Price | |
Order / More Info | RRAS2 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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