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| Antigenic Specificity | Phospho-JNK1/JNK2 (Thr183, Tyr185) |
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| Clone | E.665.10 |
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| Host Species | Mouse |
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| Reactive Species | hamster, human, mouse, rat, yeast |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | 200 µL |
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| Concentration | n/a |
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| Applications | ChIP assay: 1-3 µL, Flow Cytometry: 1:200, Immunocytochemistry: 1:400, Immunofluorescence: 1:400, Immunoprecipitation: 1:250, Western Blot: 1:1000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Phospho-JNK1/JNK2 (Thr183, Tyr185) Monoclonal Antibody (E.665.10). The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related t |
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| Immunogen | n/a |
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| Other Names | JNK-46; JNK1 alpha protein kinase; JNK1 beta protein kinase; JUN N-terminal kinase; MAP kinase 8; MAPK 8; OTTHUMP00000019552; c-Jun N-terminal kinase 1; mitogen-activated protein kinase 8 isoform JNK1 alpha1; mitogen-activated protein kinase 8 isoform JNK1 beta2; protein kinase JNK1; stress-activated protein kinase 1; stress-activated protein kinase JNK1, Phospho-JNK |
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| Gene, Accession # | Entrez: 100771734, 116554, 26419, 26420, 50658, 5599, 5601; Uniprot: P45983, P45984, P49185, P49186, Q91Y86, Q9WTU6 |
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| Catalog # | MA5-15228 |
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| Price | |
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| Order / More Info | Phospho-JNK1/JNK2 (Thr183, Tyr185) Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 25582859, 27364558 |
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