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Antigenic Specificity | Phospho-KAP-1 (Ser824) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | purified |
Size | 100 µL |
Concentration | n/a |
Applications | Immunocytochemistry: 1:200-1:1,000, Immunofluorescence: 1:200-1:1,000, Immunohistochemistry: 1:200-1:1,000, Immunoprecipitation: 2-10 µg/mg lysate, Western Blot: 1:2,000-1:10,000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Phospho-KAP-1 (Ser824) Polyclonal Antibody. The KRAB (Kruppel-associated box) domain is about 45 amino acids in length and is a transcriptional repression domain found in numerous transcription factors. There have been identified over 220 KRAB-zinc finger protein (KRAB-ZFP) genes in the human genome. These proteins functionally repress transcription via specific interactions with KAP-1 (KRAB-associated protein 1). KAP-1 is an 835 amino acid polypeptide that contains a RING finger, B boxes, and a PHD finger. KAP-1 has been shown to form complexes with KRAB-domain transcription factors and increase the efficiency with which they mediate repression. KAP-1 has also been shown to directly interact with HP1 (heterochromatin protein 1) and KRAZ1 ( |
Immunogen | n/a |
Other Names | Transcription intermediary factor 1-beta, Tripartite motif protein 28, Nuclear corepressor KAP-1, KRAB-associated protein 1, KAP-1, KRAB-interacting p |
Gene, Accession # | Entrez: 10155, 21849; Uniprot: Q13263, Q62318 |
Catalog # | A300-767A |
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Order / More Info | Phospho-KAP-1 (Ser824) Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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