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Antigenic Specificity | Phospho-JNK1/JNK2 (Thr183, Tyr185) |
Clone | F.971.6 |
Host Species | Rabbit |
Reactive Species | Drosophila, human, mouse, rat, yeast |
Isotype | IgG |
Format | purified |
Size | 100 µL |
Concentration | n/a |
Applications | Immunohistochemistry (Paraffin): 1:50, Immunoprecipitation: 1:200, Western Blot: 1:500-1:1000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Phospho-JNK1/JNK2 (Thr183, Tyr185) Monoclonal Antibody (F.971.6). The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to |
Immunogen | n/a |
Other Names | MAPK8, MAPK9, JNK, JNK-46, JNK1, JNK1A2, JNK21B1/2, PRKM8, SAPK1, SAPK1c, JUN N-terminal kinase, MAP kinase 8, c-Jun N-terminal kinase 1, mitogen-activated protein kinase 8 isoform JNK1 alpha1, mitogen-activated protein kinase 8 isoform JNK1 beta2, stress-activated protein kinase 1, stress-activated protein kinase 1c, Mitogen-activated protein kinase 9, MAP kinase 9, MAPK 9, JNK-55, Stress-activated protein kinase 1a, SAPK1a, Stress-activated protein kinase JNK2, c-Jun N-terminal kinase 2, JNK2, PRKM9, SAPK1A, Phospho-JNK |
Gene, Accession # | Entrez: 116554, 26419, 26420, 50658, 5599, 5601; Uniprot: P45983, P45984, P49185, P49186, Q91Y86, Q9WTU6 |
Catalog # | MA5-14943 |
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Order / More Info | Phospho-JNK1/JNK2 (Thr183, Tyr185) Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 26468015, 28248301 |
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