产品详情 |
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Antigenic Specificity | CD100 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 100 ug |
Concentration | n/a |
Applications | Western Blot: 1:100-1:2000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD100 Polyclonal Antibody. Semaphorins are neuronal chemorepellants that direct pioneering neurons during nervous system development. CD100 (also known as semaphorin 4d), a 150 kDa homodimer, is a novel semaphorin that induces B cells to aggregate and improves their viability in vitro. CD100 modifies CD40-CD40L B cell signaling by augmenting B cell aggregation and survival and down regulating CD23 expression. CD72 is a lymphocyte receptor for the class IV semaphorin CD100, which is involved in regulating B cell signaling. CD100 is expressed on resting and PHA stimulated T cells. The protein is weakly expressed on NK cells, EBV transformed B cells, monocytes and tumor/peripheral blood T cell lines, and at higher density on activated T cells |
Immunogen | n/a |
Other Names | Semaphorin-4D, Leukocyte activation antigen CD100, BB18, A8, GR3 |
Gene, Accession # | Entrez: 10507; Uniprot: Q92854 |
Catalog # | PA5-22804 |
Price | |
Order / More Info | CD100 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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