产品详情 |
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Antigenic Specificity | CD105 |
Clone | SN6 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | purified |
Size | 0.5 ml |
Concentration | n/a |
Applications | Flow Cytometry: Assay-Dependent |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD105 Monoclonal Antibody (SN6). CD105 or Endoglin is a Type I transmembrane protein, which is highly expressed on human vascular endothelial cells. It exists on an O- and N-glycosylated homodimer. Up regulation of endoglin expression has been demonstrated in tumor vasculature and proliferating cells, suggesting that it is a proliferation associated endothelial marker. CD105 binds to TGF beta 1 and 3 with high affinity but not to TGF beta 2. |
Immunogen | n/a |
Other Names | CD105, END, HHT1, ORW, ORW1, CD105 antigen, ENG |
Gene, Accession # | Entrez: 2022; Uniprot: P17813 |
Catalog # | MHCD10500 |
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Order / More Info | CD105 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 26065900, 27860364, 28214945, 28320483 |
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