| 产品详情 |
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| Antigenic Specificity | CD105 |
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| Clone | SN6h |
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| Host Species | Mouse |
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| Reactive Species | bovine, human |
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| Isotype | IgG1, kappa |
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| Format | purified |
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| Size | 500 µL |
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| Concentration | n/a |
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| Applications | Flow Cytometry: 0.5-1 µg/test, Immunofluorescence: 1:10-1:100, Immunohistochemistry (Paraffin): 1:100 - 200, Western Blot: 1-2 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CD105 Monoclonal Antibody (SN6h). CD105 or Endoglin or GP160 is a Type I transmembrane protein, which is highly expressed on human vascular endothelial cells. It exists as an O- and N-glycosylated homodimer. Up-regulation of endoglin expression has been demonstrated in tumor vasculature and proliferating cells, suggesting that it is a proliferation-associated endothelial cell marker. CD105 binds to TGF-Beta1 and Beta3 with high affinity but not TGF-Beta2. |
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| Immunogen | n/a |
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| Other Names | CD105, END, HHT1, ORW, ORW1, CD105 antigen, ENG |
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| Gene, Accession # | Entrez: 2022, 615844; Uniprot: P17813 |
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| Catalog # | MA5-11854 |
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| Price | |
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| Order / More Info | CD105 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 15254537, 16313759, 16650286, 16937436, 17412893, 17869000, 17932890, 18060184, 18516319, 18758639, 19434317, 21289500, 21370444, 21503229, 21689017, 22629409, 23300529, 23936513, 24125024, 24612214, 25031705, 26239842 |
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