产品详情 |
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Antigenic Specificity | CD105 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 500 µL |
Concentration | n/a |
Applications | Immunocytochemistry: 1:10-1:200, Immunofluorescence: 1:10-1:100, Immunohistochemistry (Paraffin): 1:25-1:50 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD105 Polyclonal Antibody. CD105 or Endoglin or GP160 is a Type I transmembrane protein, which is highly expressed on human vascular endothelial cells. It exists as an O- and N-glycosylated homodimer. Up-regulation of endoglin expression has been demonstrated in tumor vasculature and proliferating cells, suggesting that it is a proliferation-associated endothelial cell marker. CD105 binds to TGF-beta1 and beta3 with high affinity but not TGF-beta2. |
Immunogen | n/a |
Other Names | CD105, END, HHT1, ORW, ORW1, CD105 antigen, ENG |
Gene, Accession # | Entrez: 2022; Uniprot: P17813 |
Catalog # | PA5-16895 |
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Order / More Info | CD105 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 22235978, 26657503, 26919112 |
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