产品名称 Chk1 Antibody from INVITROGEN ANTIBODIES
产品货号 A300-161A-T
产品价格 现货询价,电话:010-67529703
产品规格 20 µL
产品品牌 INVITROGEN ANTIBODIES
产品概述
产品详情
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Antigenic SpecificityChk1
Clonepolyclonal
Host SpeciesGoat
Reactive Specieshuman
Isotypen/a
Formatpurified
Size20 µL
Concentrationn/a
ApplicationsWestern Blot: 1:1,000
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DescriptionChk1 Polyclonal Antibody. CHK1 (CHEK1) is a kinase that phosphorylates cdc25, an important phosphatase in cell cycle control, particularly for entry into mitosis. CHK1 can also phosphorylate p53 at Ser20 in vitro. Cell cycle events are regulated by the sequential activation and deactivation of cyclin dependent kinases (Cdks) and by proteolysis of cyclins. CHK1 is involved in these processes as regulators of Cdks. CHK1 function as an essential component in the G2 DNA damage checkpoint by phosphorylating Cdc25C in response to DNA damage. Phosphorylation inhibits Cdc25C activity, thereby blocking mitosis. Cdc25A, Cdc25B and Cdc25C protein tyrosine phosphatases function as mitotic activators by dephosphorylating Cdc2 p34 on regulatory tyrosine
Immunogenn/a
Other NamesCHEK1
Gene, Accession #Entrez: 1111; Uniprot: O14757
Catalog #A300-161A-T
Price
Order / More InfoChk1 Antibody from INVITROGEN ANTIBODIES
Product Specific Referencesn/a
产品资料