| 产品详情 |
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| Antigenic Specificity | Nhe-1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 20 µg/mL, Immunofluorescence: 20 µg/mL, Immunohistochemistry: 2.5 µg/mL, Western Blot: 1-2 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Nhe-1 Polyclonal Antibody. The Na+/H+ antiporter (Nhe-1) is a ubiquitous membrane-bound enzyme involved in pH regulation of vertebrate cells and is specifically inhibited by the diuretic drug amiloride and activated by a variety of signals including growth factors, mitogens, neurotransmitters, and tumor promoters. Nhe-1 acts as an anchor for actin filaments to control the integrity of the cortical cytoskeleton. This occurs through a previously unrecognized structural link between Nhe-1 and the actin-binding proteins ezrin, radixin, and moesin, collectively referred to as ERM proteins. A structural role for Nhe-1 has been proposed in regulating the cortical cytoskeleton that is independent of its function as an ion exchanger. It is also thou |
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| Immunogen | n/a |
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| Other Names | n/a |
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| Gene, Accession # | Entrez: 20544, 24782, 6548; Uniprot: P19634, P26431, Q61165 |
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| Catalog # | PA5-20444 |
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| Price | |
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| Order / More Info | Nhe-1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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