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| Antigenic Specificity | FKBP12 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 400 µL |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (Paraffin): 1:10-1:50, Western Blot: 1:1000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | FKBP12 Polyclonal Antibody. FKBP12 is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It interacts with several intracellular signal transduction proteins including type I TGF-beta receptor. It also interacts with multiple intracellular calcium release channels, and coordinates multi-protein complex formation of the tetrameric skeletal muscle ryanodine receptor. In mouse, deletion of this homologous gene causes congenital heart disorder known as noncompaction of left ventricular myocardium. |
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| Immunogen | n/a |
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| Other Names | Peptidyl-prolyl cis-trans isomerase FKBP1A; PPIase FKBP1A; EC 5.2.1.8; FK506-binding protein 1A; FKBP-1A; Rotamase; Immunophilin FKBP12; 12 kDa FKBP; FKBP-12; FKBP1A; FKBP1; FKBP12 |
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| Gene, Accession # | Entrez: 2280; Uniprot: P62942 |
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| Catalog # | PA5-14852 |
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| Price | |
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| Order / More Info | FKBP12 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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