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| Product Name | BIO-Acetoxime |
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| Description | Purity >95%. BIO-Acetoxime is an analog of the GSK3 inhibitor 6-bromoindirubin-3'-oxime, or BIO . It potently inhibits GSK3Alpha/Beta (IC50 = 10 nM), with selectivity over Cdk5/p25, Cdk2/A, and Cdk1/B (IC50 s = 2.4, 4.3, and 63 µM, respectively). BIO-Acetoxime has been used to study the role of GSK3 in the Wnt/Beta-catenin pathway. It also suppresses the cytopathic effects of herpes viruses and reduces viral yields in human oral epithelial cells. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 3-[3-[(acetyloxy)imino]-1,3-dihydro-2H-indol-2-ylidene]-6-bromo-1,3-dihydro-2H-indol-2-one, 6-Bromoindirubin-3'-acetoxime, GSK3 Inhibitor X |
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| Gene, Accession, CAS # | CAS: 740841-15-0 |
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| Catalog # | LS-H6818 |
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| Price | |
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| Order / More Info | BIO-Acetoxime from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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