产品详情 |
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Antigenic Specificity | CNR2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 100 µL |
Concentration | n/a |
Applications | Flow Cytometry: 1:50, Immunocytochemistry: 1:100, Immunofluorescence: Assay dependent, Immunohistochemistry (Frozen): 1:100, Immunohistochemistry (Paraffin): 1:100, Western Blot: 1:250-1:2500 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CNR2 Polyclonal Antibody. Cannabinoids exert their well known physiological effects through two G protein coupled receptors, cannabinoid receptor 1 (CB1) and CB2. Both cannabinoid receptors have been shown to inhibit adenylyl cyclase as well as stimulate the mitogen-activated protein kinase, MAPK. CB1 receptors also modulate ion channels through direct G-protein interactions. Delta 9-tetrahydrocannibinol and related ligands likely exert their psychoactive effects by inhibiting presynaptic N- and P/Q type calcium channels. CB2 is thought to function primarily in the immune system although it has been suggested to be present in the central nervous system, including the retina. |
Immunogen | n/a |
Other Names | CB2, Cnr2 |
Gene, Accession # | Entrez: 1269; Uniprot: P34972 |
Catalog # | PA1-744 |
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Order / More Info | CNR2 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 14657172, 14764676, 15039279, 15758162, 16754676, 21457344, 21649637, 24978314, 25704169, 27248492 |
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