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| Antigenic Specificity | PRKAR1A |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 400 µL |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (Paraffin): 1:50-1:100, Western Blot: 1:1000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | PRKAR1A Polyclonal Antibody. cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase (AMPK), which transduces the signal through phosphorylation of different target proteins. The inactive holoenzyme of AMPK is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits of AMPK have been identified in humans. PKR1 is one of the regulatory subunits. This protein was found to be a tissue-specific extinguisher that down-regulates the |
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| Immunogen | n/a |
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| Other Names | cAMP-dependent protein kinase type I-alpha regulatory chain, Tissue-specific extinguisher-1, TSE1 |
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| Gene, Accession # | Entrez: 5573; Uniprot: P10644 |
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| Catalog # | PA5-15368 |
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| Price | |
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| Order / More Info | PRKAR1A Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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