产品详情 |
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Antigenic Specificity | PRKAR2A |
Clone | H2 006 D4 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2b |
Format | purified |
Size | 100 µL |
Concentration | n/a |
Applications | ChIP assay: 1:100, Western Blot: 1:1,000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | PRKAR2A Monoclonal Antibody (H2 006 D4). The type 1(RI) and type 2 (RII) subunit of cyclic AMP-dependent protein kinase A (PKA) is a polyfunctional protein that is present in most tissues and cells. The many roles of RII include: 1) the regulation of extracellular cyclic AMP levels, 2) catalyzing the phosphorylation of the transcription factor CREB, 3) aiding in the development of mammalian oocytes and 4) phosphorylation of proteins to enhance the release of neurotransmitters. Localization of PKA is coordinated through association with A-kinase anchoring proteins (AKAPs) that bind to a 14-18aa sequence in subunit RII. |
Immunogen | n/a |
Other Names | Protein Kinase A Type 2 |
Gene, Accession # | Entrez: 5576; Uniprot: P13861 |
Catalog # | MA3-517 |
Price | |
Order / More Info | PRKAR2A Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 27891679 |
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