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| Antigenic Specificity | PRKAR1B |
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| Clone | OTI9C5 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Flow Cytometry: 1:100, Immunocytochemistry: 1:100, Immunofluorescence: 1:100, Western Blot: 1:2000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | PRKAR1B Monoclonal Antibody (OTI9C5). The second messenger cyclic AMP (cAMP) mediates diverse cellular responses to external signals such as proliferation, ion transport, regulation of metabolism and gene transcription by activation of the cAMP-dependent protein kinase (cAPK or PKA). Activation of PKA occurs when cAMP binds to the two regulatory subunits of the tetrameric PKA holoenzyme resulting in release of active catalytic subunits. Three catalytic (C) subunits have been identified that each represent specific gene products. Activation of transcription upon elevation of cAMP levels results from translocation of PKA to the nucleus where it phosphorylates the transcrip- tion factor cAMP response element binding protein (CREB) on serine 13 |
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| Immunogen | n/a |
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| Other Names | cAMP-dependent protein kinase type I-beta regulatory chain |
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| Gene, Accession # | Entrez: 5575; Uniprot: P31321 |
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| Catalog # | MA5-25526 |
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| Price | |
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| Order / More Info | PRKAR1B Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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