| 产品详情 |
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| Antigenic Specificity | Acetyl-STAT3 (Lys685) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | Western Blot: 1:1000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Acetyl-STAT3 (Lys685) Polyclonal Antibody. STAT3 belongs to the family of STAT (signal transducers and activators of transcription) proteins which are phosphorylated by receptor associated kinases, translocate to the nucleus, and act as transcription factors in response to cytokines and growth factors. Coactivators such as CREB-binding protein are required for the transcriptional activation by STAT3. STAT3 can also be activated by Interferon-alpha, Interferon-gamma, EGF, PDGF and IL6. Phosphorylation on tyrosine 705 by JAK1 and JAK2 is essential for STAT3 dimer formation, nuclear translocation, and DNA binding activity. In humans, the STAT3 gene is located on the q arm of chromosome 17. STAT3 has been shown to be activated by IFN-alpha but |
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| Immunogen | n/a |
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| Other Names | DNA-binding protein APRF; acute-phase response factor; signal transducer and activator of transcription 3 |
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| Gene, Accession # | Entrez: 20848, 25125, 6774; Uniprot: P40763, P42227, P52631 |
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| Catalog # | PA5-17429 |
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| Price | |
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| Order / More Info | Acetyl-STAT3 (Lys685) Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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