产品详情 |
Edit |   |
Antigenic Specificity | ZNF76 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | purified |
Size | 100 µl |
Concentration | n/a |
Applications | Western Blot: 1:500-1:1000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | ZNF76 Polyclonal Antibody. ZNF76, also known as ZNF523 or Zfp523, is a transcriptional repressor expressed in the testis. It is the human homolog of the Xenopus Staf protein (selenocysteine tRNA gene transcription-activating factor) known to regulate the genes encoding small nuclear RNA and selenocysteine tRNA. ZNF76 localizes to the nucleus and exerts an inhibitory function on p53-mediated transactivation. ZNF76 specifically targets TFIID (TATA-binding protein). The interaction with TFIID occurs through both its N and C termini. The transcriptional repression activity of ZNF76 is predominantly regulated by lysine modifications, acetylation and sumoylation. ZNF76 is sumoylated by PIAS 1 and is acetylated by p300. Acetylation leads to the lo |
Immunogen | n/a |
Other Names | Zinc finger protein 76; Zinc finger protein 523; ZNF76; D6S229E; ZNF523 |
Gene, Accession # | Entrez: 224656, 361809, 7629; Uniprot: B4F7E9, P36508, Q8BMU0 |
Catalog # | PA5-75844 |
Price | |
Order / More Info | ZNF76 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
产品资料 |
|
|