| 产品详情 |
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| Antigenic Specificity | CD205 |
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| Clone | NLDC-145 |
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| Host Species | Rat |
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| Reactive Species | mouse |
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| Isotype | IgG2a |
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| Format | purified |
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| Size | 2 mL |
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| Concentration | n/a |
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| Applications | Flow Cytometry: Assay Dependent, Immunocytochemistry: Assay Dependent, Immunofluorescence: Assay-dependent, Immunohistochemistry (Frozen): 1:10 -1:25 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CD205 Monoclonal Antibody (NLDC-145). CD205 (LY25, Lymphocyte Antigen 75) is an integral membrane glycoprotein involved in antigen uptake, trafficking and presentation that improves the induction of antigen-specific T cell immunity. CD205 is highly expressed by CD8+ dendritic cells (DCs) and also expressed at different levels by bone marrow Gr1+ cells, Langerhans cells, (BMDC) bone marrow derived DCs and thymic epithelial cells. CD205 acts as an endocytic receptor that directs captured antigens to the extracellular space towards a specialized antigen processing region. Further, CD205 also prompts the reduced proliferation of B lymphocytes. Diseases associated with CD205 dysfunction include pneumonic plague and lipid pneumonia. |
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| Immunogen | n/a |
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| Other Names | RP23-10L17.4, CD205, DEC-205, ly-75, CLEC13B, GP200-MR6, DCL-1 fusion, LY75-CD302 fusion protein |
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| Gene, Accession # | Entrez: 17076; Uniprot: Q60767 |
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| Catalog # | MA5-16889 |
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| Price | |
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| Order / More Info | CD205 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 12603602, 24018532 |
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