| 产品详情 |
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| Antigenic Specificity | KCNK18 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 ug |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 20 µg/mL, Immunofluorescence: 20 µg/mL, Immunohistochemistry: 5 µg/mL, Western Blot: 1-2 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | KCNK18 Polyclonal Antibody. TRESK (TWIK-related spinal cord K+ channel) is a two-pore domain K+ channel that induces outward rectification and functions as a background K+ channel that is abundantly expressed in the spinal cord, thymus, spleen, and leukemic T-lymphocytes. TRESK is activated by increased cytoplasmic calcium concentration through calcineurin as well as by acetylcholine and histamine. It has been suggested that TRESK is linked to acute and chronic pain by activation of calcineurin. Other studies indicate that TRESK may play a role in the regulation of T-cell function and could be an excellent target to treat T-cell originated immune dysfunction. |
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| Immunogen | n/a |
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| Other Names | K2p18.1, MGR13, TRESK, TRESK-2, TRESK2, TRIK; TWIK-related individual K+ channel; TWIK-related individual potassium channel; TWIK-related spinal cord K+ channel; TWIK-related spinal cord potassium channel; potassium channel subfamily K member 18 |
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| Gene, Accession # | Entrez: 332396, 338567, 445371; Uniprot: Q6Q1P3, Q6VV64, Q7Z418 |
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| Catalog # | PA5-20873 |
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| Price | |
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| Order / More Info | KCNK18 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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