| 产品详情 |
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| Antigenic Specificity | KCNQ2 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 0.5 µg/mL, Immunofluorescence: 0.5 µg/mL, Immunohistochemistry (Frozen): 0.5 µg/mL, Western Blot: Assay dependent |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | KCNQ2 Polyclonal Antibody. KCNQs are members of the voltage-dependent non-inactivating potassium channel family. Currently there are five known KNCQs (KCNQ1-5) found in the central nervous system and KNCQ2 and 3 have demonstrated their importance in M-current activation. Studies have shown that KCNQ2 and KCNQ3 form heteromultimers that, when formed, substantially increase the M-current. Inhibition of M-current controls neuron excitability throughout the nervous system as well as the responsiveness to synaptic inputs. Genetic mutations in these proteins have been linked to disorders such as benign familial neonatal convulsions (BFNC), deafness, neuropathic pain and epilepsy. |
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| Immunogen | n/a |
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| Other Names | BFNC, EBN1, ENB1, HNSPC, KCNA11, KQT like 2, KVEBN1 |
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| Gene, Accession # | Entrez: 16536, 170848, 3785; Uniprot: O43526, O88943, Q9Z351 |
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| Catalog # | PA1-929 |
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| Price | |
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| Order / More Info | KCNQ2 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 25552556, 27994149 |
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