| 产品详情 |
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| Antigenic Specificity | BCKDK |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 400 µL |
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| Concentration | n/a |
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| Applications | Immunohistochemistry: 1:50-1:100, Western Blot: 1:1000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | BCKDK Polyclonal Antibody. The second major step in the catabolism of the branched-chain amino acids, isoleucine, leucine, and valine, is irreversibly catalyzed by the branched-chain alpha-keto acid dehydrogenase complex (BCKD), an inner-mitochondrial enzyme complex composed of 3 catalytic components: a branched-chain alpha-keto acid decarboxylase (E1), a dihydrolipoyl transacylase (E2), and a dihydrolipoamide dehydrogenase (E3). The complex also contains 2 enzymes that regulated the state of activity of the BCKD complex: a kinase (BCKDK), and a phosphorylase. The ubiquitiously expressed kinase contains 1 histidine kinase domain. Maple syrup urine disease (MSUD) is a pathology secondary to an enzyme defect in the catabolic pathway of leucin |
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| Immunogen | n/a |
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| Other Names | 3-methyl-2-oxobutanoate dehydrogenase lipoamide kinase, mitochondrial; Branched-chain alpha-ketoacid dehydrogenase kinase; BCKDHKIN; BCKD-kinase |
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| Gene, Accession # | Entrez: 10295; Uniprot: O14874 |
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| Catalog # | PA5-13903 |
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| Price | |
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| Order / More Info | BCKDK Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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