产品详情 |
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Antigenic Specificity | Bcl-10 |
Clone | 151 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | ELISA: Assay-dependent, Flow Cytometry: Assay-dependent, Immunohistochemistry (Paraffin): Assay-dependent, Immunoprecipitation: Assay-dependent, Western Blot: Assay-dependent |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Bcl-10 Monoclonal Antibody (151). BCL-10 is an N-terminal CARD (Caspase Recruitment Domain) containing protein that is involved in the adaptive immune response. It promotes apoptosis, pro-caspase-9 maturation, and activation of NF-kappa-B via NIK and IKK. BCL-10 is also an adapter protein between upstream TNFR1-TRADD-RIP complex and the downstream NIK-IKK-IKAP complex. It is a substrate for MALT1. Mutations in the gene can lead to Immunodeficiency 37 or Lymphoma, mucosa-associated lymphoid type. |
Immunogen | n/a |
Other Names | n/a |
Gene, Accession # | Entrez: 8915; Uniprot: O95999 |
Catalog # | MA5-28142 |
Price | |
Order / More Info | Bcl-10 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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