产品详情 |
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Antigenic Specificity | Bcl-10 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | Western Blot: Assay Dependent |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Bcl-10 Polyclonal Antibody. BCL-10 is an N-terminal CARD (Caspase Recruitment Domain) containing protein that is involved in the adaptive immune response. It promotes apoptosis, pro-caspase-9 maturation, and activation of NF-kappa-B via NIK and IKK. BCL-10 is also an adapter protein between upstream TNFR1-TRADD-RIP complex and the downstream NIK-IKK-IKAP complex. It is a substrate for MALT1. Mutations in the gene can lead to Immmunodeficiency 37 or Lymphoma, mucosa-associated lymphoid type. |
Immunogen | n/a |
Other Names | B-cell CLL/lymphoma 10, Bcl-10 CED-3/ICH-1 prodomain homologous E10-like regulator, CIPER |
Gene, Accession # | Entrez: 8915; Uniprot: O95999 |
Catalog # | PA1-12513 |
Price | |
Order / More Info | Bcl-10 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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