产品详情 |
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Antigenic Specificity | Bcl-10 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | purified |
Size | 100 ug |
Concentration | n/a |
Applications | Immunocytochemistry: 1 µg/mL, Immunofluorescence: 10 µg/mL, Western Blot: 0.5 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Bcl-10 Polyclonal Antibody. BCL-10 is an N-terminal CARD (Caspase Recruitment Domain) containing protein that is involved in the adaptive immune response. It promotes apoptosis, pro-caspase-9 maturation, and activation of NF-kappa-B via NIK and IKK. BCL-10 is also an adapter protein between upstream TNFR1-TRADD-RIP complex and the downstream NIK-IKK-IKAP complex. It is a substrate for MALT1. Mutations in the gene can lead to Immmunodeficiency 37 or Lymphoma, mucosa-associated lymphoid type. |
Immunogen | n/a |
Other Names | RP11-234D19.2, CARMEN, CIPER, CLAP, c-E10, mE10; B-cell lymphoma/leukemia 10; CARD containing molecule enhancing NF-kB; CARD-containing apoptotic signaling protein; CARD-containing molecule enhancing NF-kappa-B; CARD-containing proapoptotic protein; CED-3/ICH-1 prodomain homologous E10-like regulator; cCARMEN; caspase-recruiting domain-containing protein; cellular homolog of vCARMEN; cellular-E10; hCLAP; mammalian CARD-containing adapter molecule E10 |
Gene, Accession # | Entrez: 12042, 83477, 8915; Uniprot: O95999, Q9QYN5, Q9Z0H7 |
Catalog # | PA5-19931 |
Price | |
Order / More Info | Bcl-10 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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