产品详情 |
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Antigenic Specificity | CD28 |
Clone | 10F3 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | phycoerythrin (PE) conjugate |
Size | 0.5 ml |
Concentration | n/a |
Applications | Flow Cytometry: Assay-Dependent |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD28 Monoclonal Antibody (10F3), PE. CD28 antigen is a 44 kDa disulfide linked homodimeric T cell specific surface glycoprotein. CD28 is a cell adhesion molecule of the immunoglobulin superfamily which is constitutively expressed on most peripheral blood T lymphocytes. Moreover, CD28 is the critical T cell costimulatory receptor that provides the cell the important second activation signal by binding CD80 and CD86 which are expressed by antigen presenting cells. In addition to its co-stimulation role, CD28 functions by preventing T cells from entering an anergic-hyporesponsive state or from undergoing premature apoptotic cell death. In murine peripheral lymphoid organs and in the blood, all CD4+ and CD8+ T cells express CD28. In the thymus, |
Immunogen | n/a |
Other Names | MGC138290, Tp44, CD28 antigen, T-cell-specific surface glycoprotein CD28 |
Gene, Accession # | Entrez: 940; Uniprot: P10747 |
Catalog # | CD2804 |
Price | |
Order / More Info | CD28 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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