产品详情 |
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Antigenic Specificity | Angiotensin |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 400 µL |
Concentration | n/a |
Applications | Immunohistochemistry: 1:10-1:50, Western Blot: 1:1000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Angiotensin Polyclonal Antibody. AGT, pre-angiotensinogen or angiotensinogen precursor, is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. The resulting product, angiotensin I, is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. The protein is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia. Mutations in AGT gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in AGT gene have also been associated with non-familial structural atrial fibrillation, and inflammatory |
Immunogen | n/a |
Other Names | Angiotensinogen; Serpin A8; Angiotensin-1; Angiotensin I; Ang I; Angiotensin-2; Angiotensin II; Ang II; Angiotensin-3; Angiotensin III; Ang III; Des-Asp[1]-angiotensin II; AGT; SERPINA8 |
Gene, Accession # | Entrez: 183; Uniprot: P01019 |
Catalog # | PA5-15012 |
Price | |
Order / More Info | Angiotensin Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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