| 产品详情 |
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| Antigenic Specificity | Angiotensinogen |
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| Clone | 754438 |
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| Host Species | Rat |
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| Reactive Species | mouse |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | lyophilized |
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| Applications | Immunohistochemistry (Frozen): 8-25 µg/mL, Western Blot: 0.5 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Angiotensinogen Monoclonal Antibody (754438). The protein encoded by this gene, pre-angiotensinogen or angiotensinogen precursor, is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. The resulting product, angiotensin I, is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. The protein is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia. Mutations in this gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial struc |
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| Immunogen | n/a |
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| Other Names | AGT, Angiotensin I, ANHU, Angiotensinogen, Pre-angiotensinogen, Angiotensin II, SERPINA8, Serpin A8 |
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| Gene, Accession # | Entrez: 11606; Uniprot: P11859 |
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| Catalog # | MA5-24361 |
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| Price | |
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| Order / More Info | Angiotensinogen Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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