| 产品详情 |
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| Antigenic Specificity | Agrin |
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| Clone | Agr 247 |
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| Host Species | Mouse |
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| Reactive Species | mouse, rat |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 2 µg/mL, Immunofluorescence: Assay dependent |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Agrin Monoclonal Antibody (Agr 247). Agrin is an essential extracellular matrix component which promotes clustering of nicotinic acetylcholine receptors (nAChRs) and other proteins during development at the neuromuscular junction. Agrin, MuSK and Rapsyn are all essential components for AChR aggregation, through an unknown mechanism. The C-terminal region of agrin is released into the medium, interacts with receptors on the muscle surface and induces AChR aggregation. The central region contains two O-linked glycosylation sites and a domain homologous to domain III of laminin. The N-terminal region anchors agrin to the extracellular matrix via other basal membrane components. This region also contains a protease inhibitor domain and glycosam |
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| Immunogen | n/a |
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| Other Names | RP23-139J18.2, Agrin |
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| Gene, Accession # | Entrez: 11603, 25592; Uniprot: A2ASQ1, P25304 |
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| Catalog # | MA1-20380 |
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| Price | |
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| Order / More Info | Agrin Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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