产品详情 |
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Antigenic Specificity | Cutaneous Lymphocyte Antigen (CLA) |
Clone | HECA-452 |
Host Species | Rat |
Reactive Species | human |
Isotype | IgM, kappa |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | Flow Cytometry: 0.125 µg/test, Functional Assay: Assay-Dependent, Immunohistochemistry (Paraffin): 10 µg/mL, Western Blot: Assay-Dependent |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Cutaneous Lymphocyte Antigen (CLA) Monoclonal Antibody (HECA-452), eBioscience™. This cell surface glycoprotein is most highly expressed on T cells in the skin. Nevertheless, CLA can also be detected on some peripheral T and NK cells, as well as monocytes, neutrophils and CD1a+ dendritic cells. Studies have determined that this antibody recognizes sialofucosylated glycans and sialyl Lewis x (sLex). CLA, which binds E-selectin and endothelial cell-leukocyte adhesion molecule 1 (ELAM-1), is involved in T lymphocyte infiltration and adhesion at cutaneous sites of inflammation. |
Immunogen | n/a |
Other Names | CLA |
Gene, Accession # | n/a |
Catalog # | 14-9857-82 |
Price | |
Order / More Info | Cutaneous Lymphocyte Antigen (CLA) Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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