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Antigenic Specificity | Cutaneous Lymphocyte Antigen (CLA) |
Clone | HECA-452 |
Host Species | Rat |
Reactive Species | human, nonhuman primate |
Isotype | IgM, kappa |
Format | eFluor 660 conjugate |
Size | 25 µg |
Concentration | n/a |
Applications | Flow Cytometry: 20 µg/mL, Functional Assay: Assay-Dependent, Immunocytochemistry: Assay-Dependent, Immunofluorescence: Assay-Dependent, Immunohistochemistry (Paraffin): Assay-Dependent, Western Blot: Assay-Dependent |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Cutaneous Lymphocyte Antigen (CLA) Monoclonal Antibody (HECA-452), eFluor 660, eBioscience™. This cell surface glycoprotein is most highly expressed on T cells in the skin. Nevertheless, CLA can also be detected on some peripheral T and NK cells, as well as monocytes, neutrophils and CD1a+ dendritic cells. Studies have determined that this antibody recognizes sialofucosylated glycans and sialyl Lewis x (sLex). CLA, which binds E-selectin and endothelial cell-leukocyte adhesion molecule 1 (ELAM-1), is involved in T lymphocyte infiltration and adhesion at cutaneous sites of inflammation. |
Immunogen | n/a |
Other Names | CLA |
Gene, Accession # | n/a |
Catalog # | 50-9857-80 |
Price | |
Order / More Info | Cutaneous Lymphocyte Antigen (CLA) Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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