| 产品详情 |
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| Antigenic Specificity | LXR alpha |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | Western Blot: 1:1000-1:10,000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | LXR alpha Polyclonal Antibody. The liver X receptors, LXRA and LXRB (NR1H2; MIM 600380), form a subfamily of the nuclear receptor superfamily and are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. The inducible LXRA is highly expressed in liver, adrenal gland, intestine, adipose tissue, macrophages, lung, and kidney, whereas LXRB is ubiquitously expressed. Ligand-activated LXRs form obligate heterodimers with retinoid X receptors (RXRs; see MIM 180245) and regulate expression of target genes containing LXR response elements (summary by Korf et al., 2009 [PubMed 19436111]). |
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| Immunogen | n/a |
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| Other Names | LXR-a, LXRA, RLD-1, liver X nuclear receptor alpha variant 1, oxysterols receptor LXR-alpha |
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| Gene, Accession # | Entrez: 10062; Uniprot: Q13133 |
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| Catalog # | PA5-29868 |
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| Price | |
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| Order / More Info | LXR alpha Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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