| 产品详情 |
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| Antigenic Specificity | LXR beta |
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| Clone | K8917 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG2a |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | ELISA: Assay Dependent, Immunoprecipitation: Assay Dependent, Western Blot: Assay Dependent |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | LXR beta Monoclonal Antibody (K8917). LXR-B belongs to the Liver X Receptor family that encodes highly homologous transcription factors. Like the highly homologous LXR-A, LXR-B forms heterodimers with the retinoic acid receptor RXRalpha, which function as sensors for cellular oxysterols which when activated, increase the expression of genes that control sterol and fatty acid metabolism and homeostasis. Recent experiments have indicated that the LXRs can also modulate both innate and adaptive immune responses. Other studies suggest that genetic variability at the LXR-B gene locus may be a risk factor for Alzheimer's disease. One hypothesis postulates that LXR may be upstream of ApoE and potentiates the risk associated effects of the epsilon3 |
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| Immunogen | n/a |
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| Other Names | LXR-b, LXRB, NER, NER-I, RIP15, UNR, LX receptor beta, liver X nuclear receptor beta, liver X receptor beta, liver X receptor-beta, nuclear orphan receptor LXR-beta, nuclear receptor NER, oxysterols receptor LXR-beta, steroid hormone-nuclear receptor NER, ubiquitously-expressed nuclear receptor |
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| Gene, Accession # | Entrez: 7376; Uniprot: P55055 |
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| Catalog # | 418400 |
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| Price | |
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| Order / More Info | LXR beta Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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