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| Product Name | HTS01037 |
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| Description | Purity >98% (NMR, HPLC). HTS01037 inhibits fatty acid binding proteins. Inhibits lipolysis in 3T3-L1 adipocytes and reduces LPS-stimulated inflammation in cultured macrophages. Acts as an antagonist of the protein-protein interaction between AFABP/aP2 and hormone sensitive lipase but does not activate PPARg in macrophages. Inhibits FABP-dependent and fatty acid-stimulated leukotriene C4 biosynthesis. Reduces intracellular free fatty acid levels, lowering macrophage inflammation and ER stress. Reduces LPS-stimulated IL-1b secretion in a mouse model. Inhibits VLDL-induced foam cell formation. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 4-[(3-Carboxy-1-oxo-2-propen-1-yl)amino]-[2,2'-bithiophene]-5-carboxylic acid, 5-methyl ester |
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| Gene, Accession, CAS # | CAS: 682741-29-3 |
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| Catalog # | LS-H14706 |
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| Order / More Info | HTS01037 from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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