| 产品详情 |
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| Antigenic Specificity | DDIT4 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 400 µL |
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| Concentration | n/a |
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| Applications | Flow Cytometry: 1:10-1:50, Immunohistochemistry: 1:10-1:50, Western Blot: 1:1000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | DDIT4 Polyclonal Antibody. REDD1 is a novel transcriptional target of p53 induced following DNA damage. During embryogenesis, REDD1 expression mirrors the tissue-specific pattern of the p53 family member p63, and TP63 null embryos show virtually no expression of REDD1, which is restored in mouse embryo fibroblasts following p63 expression. In differentiating primary keratinocytes, TP63 and REDD1 expression are coordinately downregulated, and ectopic expression of either gene inhibits in vitro differentiation. REDD1 appears to function in the regulation of reactive oxygen species (ROS); TP63 null fibroblasts have decreased ROS levels and reduced sensitivity to oxidative stress, which are both increased following ectopic expression of either |
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| Immunogen | n/a |
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| Other Names | Protein regulated in development and DNA damage response 1; REDD-1; HIF-1 responsive protein RTP801 |
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| Gene, Accession # | Entrez: 54541; Uniprot: Q9NX09 |
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| Catalog # | PA5-13253 |
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| Price | |
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| Order / More Info | DDIT4 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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